**Job Description**

The laboratory studies human brain development and neuropsychiatric disease using stem cell–derived organoids and primary fetal tissue. Current projects focus on:

+ Defining how radial glia give rise to hippocampal and neocortical lineages, and identifying signaling pathways (e.g., Wnt and beyond) that govern hippocampal subfield specification
+ Building and characterizing human hippocampal organoid systems, including efforts to engineer missing subfields (e.g., CA1/CA3/DG)
+ Identifying conserved molecular and cellular programs across genetic and pharmacologic models of schizophrenia using large-scale single-cell and multiomic datasets
+ Modeling neurodevelopmental contributions to schizophrenia through perturbation systems, including chronic and acute NMDA receptor inhibition (e.g., ketamine exposure)
+ Developing scalable perturbation platforms (e.g., inducible CRISPRa/i systems) to systematically interrogate candidate regulatory pat...