Background:
The SG-Microbiome / GLOW programme is a multi-site effort to generate an integrated, multi-modal dataset spanning population cohort data, mental health and behavioural insights, host molecular phenotyping, microbiome phenotyping, and other multi-omics. Work Package 5 (WP5) provides the data integration and platform backbone for the programme by establishing a secure, scalable compute-and-data environment, implementing reproducible processing pipelines, and enabling harmonized, analysis-ready datasets for downstream statistical and machine learning analyses across WP1-WP4.

WP5 will adopt an AWS-native approach in the first instance, dovetailing into PRECISE?s existing data infrastructure to benefit from shared capabilities and economies of scale. In parallel, WP5 will evaluate (and, if approved, integrate with) Trusted Research Environments (TREs) such as MOH TRUST and BC Platforms to support governed access, secure collaboration, and potential federa...