RESEARCH FELLOW

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**Responsibilities***

A post-doctoral position is immediately available to investigate how tumor microenvironment and neurodevelopment influence diffuse midline glioma (DMG) biology and therapeutic response. This project places a strong emphasis on orthotopic mouse modeling of brain tumors, including brainstem implantation, integrated with mechanistic cell-based studies and rigorous in vivo therapeutic testing.

Under the supervision of Dr. Koschmann (Department of Pediatrics), the fellow will lead the development and application of advanced genetically engineered and orthotopic murine models, including intra-uterine electroporation (IUE)?based systems and brainstem tumor implantation approaches that faithfully recapitulate human DMG. A major focus of the position will be the design, execution, and analysis of in vivo treatment studies, including evaluation of novel targeted and epigenetic therapies using survival, imaging, m...