The Masle-Farquhar Laboratory sits within the Translational Genomics Program. Supported by NHMRC, NSW OHMR, Garvan, Arthritis Australia and the Exceptional Responders Program, the Masle-Farquhar “Arthritis & Immunogenomics Laboratory” studies mechanisms and novel treatments of immune diseases, with a major focus on arthritic diseases: osteoarthritis, rheumatoid and psoriatic arthritis, gout and others. We are rapidly growing a tissue biobank that is unique within NSW, and storing precious tissue samples that are normally discarded during patients’ hospital procedures, from >300 patients to date.

We apply cutting-edge immunology, genomics and multiomics methods to patients’ tissue samples, to reveal the underlying drivers of arthritic diseases. Working with Garvan Biologics, we are co-

designing and producing novel antibodies and small molecule inhibitors, for pre-clinical testing in bespoke mouse models of pathology. Working with >30 clinicians in Sydney and...