Position Overview
Essential Duties and responsibilities
Responsible for the design, analysis, interpretation, and reporting of preclinical, clinical DMPK and clinical pharmacology data generated at external vendors and academic sites Serve as a primary source of scientific expertise for the design, analysis, reporting and presentation of pharmacokinetic and pharmacodynamic modeling and simulation data Provide DMPK guidance for hit to lead and lead optimization in discovery programs. Support tox studies by guiding BA method development and validation as well as TK analysis. Prepare strategic and scientifically sophisticated DMPK and clinical pharmacology drug development strategies that meet regulatory requirements and program goals Participate in the management of CROs and academic sites in the conduct of in vitro/in vivo ADME, DMPK and clinical pharmacology studies Design and oversee clinical food effects, drug-drug interac...