We are seeking a highly enthusiastic postdoctoral fellow. The Dibra lab is highly collaborative, innovation-driven lab pushing the boundaries of tumor immunology. Our work spans the full arc, from cutting-edge genetic screens and spatial multi-omics to functional in vivo validation, all aimed at cracking the code of how tumors evade the immune system.

We leverage advanced in vivo genetic screening platforms, such as Perturb-map, with spatially resolved perturbations to map tumor–immune interactions at unprecedented resolution. Using single-cell and spatial transcriptomics (including Xenium), we decode cellular heterogeneity, immune niche architecture, and lineage states within the tumor microenvironment. A core focus is understanding how oncogenes actively hijack both innate and adaptive immunity — and how we can stop them. We pair this with immunopeptidomics to uncover tumor-specific antigen presentation dynamics and identify new therapeutic vulnerabilities. Under...